---

Track your Biohacking Protocols & Supplements with a Biohacking AI Coach Biohackr IOS app

---

Your Guide to Nobiletin: Benefits, Dosage, and More

Looking to optimize your health or performance with Nobiletin? This guide breaks down everything you need to know about this popular flavonoid, from its benefits and dosage to the latest research and biohacker insights.

---

What is Nobiletin?

Nobiletin is a natural polymethoxyflavone found primarily in citrus fruits, particularly in the peels of tangerines and oranges. It is known for its diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties.

---

Key Potential Benefits & Uses

Based on research and biohacker experiences, Nobiletin is often used for:

• Cognitive Enhancement: May support memory, learning, and overall brain function.
• Circadian Rhythm Regulation: Emerging research suggests potential benefits for adjusting sleep-wake cycles.
• Metabolic Health: May help regulate blood sugar and lipid metabolism.
• Antioxidant & Anti-inflammatory: Possesses properties that can help combat oxidative stress and inflammation in the body.
• Mechanism: Works through various pathways, including modulating signaling pathways involved in neuroprotection, metabolism, and circadian clock genes.

---

Scientific Evidence: What Does the Research Say?

• Emerging evidence from animal studies and some preliminary human trials suggests Nobiletin has potential benefits for cognitive function, metabolic health, and circadian rhythm regulation. More robust human clinical trials are needed to confirm these effects.
• Strength of Evidence: Emerging

---

How to Take Nobiletin

• Common Forms: Capsules, Powder.
• Typical Dosage: 50-500 mg per day. Consult a healthcare professional for personalized dosage advice.
• Timing: Often taken in the morning or as recommended by a healthcare professional.
• Bioavailability Tips: Taking Nobiletin with a source of healthy fats may enhance its absorption.

---

Synergies & Stacking

• Nobiletin is often stacked with other cognitive enhancers like Alpha-GPC or Lion's Mane, or with supplements targeting metabolic health like Berberine.

---

Potential Side Effects & Precautions

Like any supplement, Nobiletin may cause side effects, though they are typically rare. These can include:

• Digestive Upset: Mild stomach discomfort may occur in some individuals.
• [Precautions]: Consult a healthcare professional before taking Nobiletin, especially if you are pregnant, breastfeeding, have underlying health conditions, or are taking medications.

---

Choosing the Right Form & Quality

• Quality Tips: Look for products that are third-party tested for purity and potency. Ensure the source is reputable.

---

Biohacker Insights & Community Experiences

• Common Experiences: Some users report subjective improvements in focus, alertness, and mood, particularly when taken consistently.
• Pro Tip: Experiment with timing (morning vs. evening) to see how it affects your energy levels and sleep cycle.

---

Frequently Asked Questions (FAQs)

• Is Nobiletin safe?
  • Answer: Nobiletin is generally considered safe at typical supplement dosages, but always consult a healthcare professional before use.
• How long does it take to see effects from Nobiletin?
  • Answer: Effects can vary, with some reporting acute benefits for focus while others note more subtle changes in mood or metabolic markers over weeks of consistent use.

---

Disclaimer

This guide is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any new supplement, especially if you have underlying health conditions or are taking medications.